Publications

2016

Systematic identification of phenotypically enriched loci using a patient network of genomic disorders.

Reyes-Palomares A, Bueno A, Rodríguez-López R, Medina MÁ, Sánchez-Jiménez F, Corpas M, Ranea JA.

BMC Genomics. 2016 Mar 15;17(1):232. doi: 10.1186/s12864-016-2569-6.

Amplification of actin polymerization forces.

Dmitrieff S, Nédélec F.

J Cell Biol. 2016 Mar 28;212(7):763-6. doi: 10.1083/jcb.201512019.

A genetic interaction map of cell cycle regulators.

Billmann M, Horn T, Fischer B, Sandmann T, Huber W, Boutros M.

Mol Biol Cell. 2016 Apr 15;27(8):1397-407. doi: 10.1091/mbc.E15-07-0467.

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.

Isokane M, Walter T, Mahen R, Nijmeijer B, Hériché JK, Miura K, Maffini S, Ivanov MP, Kitajima TS, Peters JM, Ellenberg J.

J Cell Biol. 2016 Mar 14;212(6):647-59. doi: 10.1083/jcb.201408089.

Sister chromatid resolution is an intrinsic part of chromosome organization in prophase.

Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T.

Nat Cell Biol. 2016 Jun;18(6):692-9.

The cellular microscopy phenotype ontology.

Jupp S, Malone J, Burdett T, Heriche JK, Williams E, Ellenberg J, Parkinson H, Rustici G.

J Biomed Semantics. 2016 May 18;7:28. doi: 10.1186/s13326-016-0074-0. eCollection 2016.

Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission.

Uehara R, Kamasaki T, Hiruma S, Poser I, Yoda K, Yajima J, Gerlich DW, Goshima G.

Mol Biol Cell. 2016 Jan 13. pii: mbc.E15-02-0101.

An analysis toolbox to explore mesenchymal migration heterogeneity reveals adaptive switching between distinct modes.

Shafqat-Abbasi H, Kowalewski JM, Kiss A, Gong X, Hernandez-Varas P, Berge U, Jafari-Mamaghani M, Lock JG, Strömblad S.

Elife. 2016 Jan 29;5. pii: e11384. doi: 10.7554/eLife.11384.

2015

Waterpixels.

Machairas V, Faessel M, Cárdenas-Peña D, Chabardes T, Walter T, Decencière E.

IEEE Trans Image Process. 2015 Nov;24(11):3707-16. doi: 10.1109/TIP.2015.2451011.

An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis.

Guglielmi G, Barry JD, Huber W, De Renzis S.

Dev Cell. 2015 Nov 18. pii: S1534-5807(15)00685-1. doi: 10.1016/j.devcel.2015.10.020.

A chemical-genetic interaction map of small molecules using high-throughput imaging in cancer cells.

Breinig M, Klein FA, Huber W, Boutros M.

Mol Syst Biol. 2015 Dec 23;11(12):846. doi: 10.15252/msb.20156400

SiR-Hoechst is a far-red DNA stain for live-cell nanoscopy.

Lukinavičius G, Blaukopf C, Pershagen E, Schena A, Reymond L, Derivery E, Gonzalez-Gaitan M, D'Este E, Hell SW, Gerlich DW, Johnsson K.

Nat Commun. 2015 Oct 1;6:8497. doi: 10.1038/ncomms9497.

Membrane Mechanics of Endocytosis in Cells with Turgor.

Dmitrieff S, Nédélec F.

PLoS Comput Biol. 2015 Oct 30;11(10):e1004538. doi: 10.1371/journal.pcbi.1004538

TimerQuant: A modelling approach to tandem fluorescent timer design and data interpretation for measuring protein turnover in embryos.

Barry JD, Donà E, Gilmour D, Huber W.

Development. 2015 Nov 24. pii: dev.125971.

A cell-based model system links chromothripsis with hyperploidy.

Mardin BR, Drainas AP, Waszak SM, Weischenfeldt J, Isokane M, Stütz AM, Raeder B, Efthymiopoulos T, Buccitelli C, Segura-Wang M, Northcott P, Pfister SM, Lichter P, Ellenberg J, Korbel JO.

Mol Syst Biol. 2015 Sep 28;11(9):828. doi: 10.15252/msb.20156505

The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration.

Peeters MC, Fokkelman M, Boogaard B, Egerod KL, van de Water B, IJzerman AP, Schwartz TW.

Cell Signal. 2015 Aug 29. pii: S0898-6568(15)00246-6. doi: 10.1016/j.cellsig.2015.08.015

Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose-response data.

Mpindi JP, Swapnil P, Dmitrii B, Jani S, Saeed K, Wennerberg K, Aittokallio T, Östling P, Kallioniemi O.

Bioinformatics. 2015 Aug 7. pii: btv455

Identifying and characterising key alternative splicing events in Drosophila development.

Lees JG, Ranea JA, Orengo CA.

BMC Genomics. 2015 Aug 16;16(1):608. doi: 10.1186/s12864-015-1674-2

Disentangling Membrane Dynamics and Cell Migration; Differential Influences of F-actin and Cell-Matrix Adhesions

Jacob M. Kowalewski, Hamdah Shafqat-Abbasi, Mehrdad Jafari-Mamaghani, Bereket Endrias Ganebo, Xiaowei Gong, Staffan Strömblad, John G. Lock Research Article | published 06 Aug 2015 | PLOS ONE 10.1371/journal.pone.0135204

An open data ecosystem for cell migration research.

Masuzzo P, Martens L; 2014 Cell Migration Workshop Participants, Ampe C, Anderson KI, Barry J, De Wever O, Debeir O, Decaestecker C, Dolznig H, Friedl P, Gaggioli C, Geiger B, Goldberg IG, Horn E, Horwitz R, Kam Z, Le Dévédec SE, Vignjevic DM, Moore J, Olivo-Marin JC, Sahai E, Sansone SA, Sanz-Moreno V, Strömblad S, Swedlow J, Textor J, Van Troys M, Zantl R.

Trends Cell Biol. 2015 Feb;25(2):55-8. doi: 10.1016/j.tcb.2014.11.005. Epub 2014 Dec 5.

Chromosome Missegregation Associated with RUVBL1 Deficiency.

Gentili C, Castor D, Kaden S, Lauterbach D, Gysi M, Steigemann P, Gerlich DW, Jiricny J, Ferrari S.

PLoS One. 2015 Jul 22;10(7):e0133576. doi: 10.1371/journal.pone.0133576. eCollection 2015.

A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime.

Hernández-Varas P, Berge U, Lock JG, Strömblad S.

Nat Commun. 2015 Jun 25;6:7524. doi: 10.1038/ncomms8524

A generic methodological framework for studying single cell motility in high-throughput time-lapse data.

Schoenauer Sebag A, Plancade S, Raulet-Tomkiewicz C, Barouki R, Vert JP, Walter T.

Bioinformatics. 2015 Jun 15;31(12):i320-i328. doi: 10.1093/bioinformatics/btv225.

Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells.

Boni A, Politi AZ, Strnad P, Xiang W, Hossain MJ, Ellenberg J.

J Cell Biol. 2015 Jun 8;209(5):705-20. doi: 10.1083/jcb.201409133.

Geometrical and mechanical properties control actin filament organization.

Letort G, Politi AZ, Ennomani H, Théry M, Nedelec F, Blanchoin L.

PLoS Comput Biol. 2015 May 27;11(5):e1004245. doi: 10.1371/journal.pcbi.1004245. eCollection 2015 May.

Non-monotonic cellular responses to heterogeneity in talin protein expression-level.

Kiss A, Gong X, Kowalewski JM, Shafqat-Abbasi H, Strömblad S, Lock JG.

Integr Biol (Camb). 2015 May 22.

Advanced microscopy methods for visualizing chromatin structure.

Lakadamyali M, Cosma MP.

FEBS Lett. 2015 Apr 17. pii: S0014-5793(15)00250-1. doi: 10.1016/j.febslet.2015.04.012.

Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant.

van Roosmalen W, Le Dévédec SE, Golani O, Smid M, Pulyakhina I, Timmermans AM, Look MP, Zi D, Pont C, de Graauw M, Naffar-Abu-Amara S, Kirsanova C, Rustici G, Hoen PA, Martens JW, Foekens JA, Geiger B, van de Water B.

J Clin Invest. 2015 Apr 1;125(4):1648-64. doi: 10.1172/JCI74440.

Cellular phenotype database: a repository for systems microscopy data.

Kirsanova C, Brazma A, Rustici G, Sarkans U.

Bioinformatics. 2015 Apr 9. pii: btv199.

High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells.

Wachsmuth M, Conrad C, Bulkescher J, Koch B, Mahen R, Isokane M, Pepperkok R, Ellenberg J.

Nat Biotechnol. 2015 Apr;33(4):384-9. doi: 10.1038/nbt.3146. Epub 2015 Mar 16.

Chromatin fibers are formed by heterogeneous groups of nucleosomes in vivo.

Ricci MA, Manzo C, García-Parajo MF, Lakadamyali M, Cosma MP.

Cell. 2015 Mar 12;160(6):1145-58. doi: 10.1016/j.cell.2015.01.054.

A map of directional genetic interactions in a metazoan cell.

Fischer B, Sandmann T, Horn T, Billmann M, Chaudhary V, Huber W, Boutros M.

Elife. 2015 Mar 6;4. doi: 10.7554/eLife.05464

FUN-L: Gene prioritization for RNAi screens.

Lees JG, Hériché JK, Morilla I, Fernández JM, Adler P, Krallinger M, Vilo J, Valencia A, Ellenberg J, Ranea JA, Orengo C.

Bioinformatics. 2015 Feb 8. pii: btv073. [Epub ahead of print]

2014

Assessment of algorithms for mitosis detection in breast cancer histopathology images.

Veta M, van Diest PJ, Willems SM, Wang H, Madabhushi A, Cruz-Roa A, Gonzalez F, Larsen AB, Vestergaard JS, Dahl AB, Cireşan DC, Schmidhuber J, Giusti A, Gambardella LM, Tek FB, Walter T, Wang C, Kondo S, Matuszewski BJ, Precioso F, Snell V, Kittler J, de Campos TE, Khan AM, Rajpoot NM, Arkoumani E, Lacle MM, Viergever MA, Pluim JP.

Med Image Anal. 2014 Nov 29. pii: S1361-8415(14)00180-7. doi: 10.1016/j.media.2014.11.010

Mechanical design principles of a mitotic spindle.

Ward JJ, Roque H, Antony C, Nedelec FJ.

Elife. 2014 Dec 18;3. doi: 10.7554/eLife.03398.

A microfluidic platform for correlative live-cell and super-resolution microscopy.

Tam J, Cordier GA, Bálint Š, Sandoval Álvarez Á, Borbely JS, Lakadamyali M.

PLoS One. 2014 Dec 29;9(12):e115512. doi: 10.1371/journal.pone.0115512.

Protein quality control at the inner nuclear membrane.

Khmelinskii A, Blaszczak E, Pantazopoulou M, Fischer B, Omnus DJ, Le Dez G, Brossard A, Gunnarsson A, Barry JD, Meurer M, Kirrmaier D, Boone C, Huber W, Rabut G, Ljungdahl PO, Knop M.

Nature. 2014 Dec 18;516(7531):410-3. doi: 10.1038/nature14096.

Cytokinetic Abscission: Molecular Mechanisms and Temporal Control.

Mierzwa B, Gerlich DW.

Dev Cell. 2014 Dec 8;31(5):525-538. doi: 10.1016/j.devcel.2014.11.006. Review.

Androgen receptor interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen-deficient conditions.

Saeed K, Ostling P, Björkman M, Mirtti T, Alanen K, Vesterinen T, Sankila A, Lundin J, Lundin M, Rannikko A, Nordling S, Mpindi JP, Kohonen P, Iljin K, Kallioniemi O, Rantala JK.

Int J Cancer. 2014 Oct 30. doi: 10.1002/ijc.29303

Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells.

Mahen R, Koch B, Wachsmuth M, Politi AZ, Perez-Gonzalez A, Mergenthaler J, Cai Y, Ellenberg J.

Mol Biol Cell. 2014 Sep 17. pii: mbc.E14-06-1091.

Positive feedback between golgi membranes, microtubules and ER-exit sites directs golgi de novo biogenesis.

Ronchi P, Tischer C, Acehan D, Pepperkok R.

J Cell Sci. 2014 Sep 4. pii: jcs.150474.

Measuring genetic interactions in human cells by RNAi and imaging.

Laufer C, Fischer B, Huber W, Boutros M.

Nat Protoc. 2014 Oct;9(10):2341-53. doi: 10.1038/nprot.2014.

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration.

Yizhak K, Le Dévédec SE, Rogkoti VM, Baenke F, de Boer VC, Frezza C, Schulze A, van de Water B, Ruppin E.

Mol Syst Biol. 2014 Aug 1;10(8):744. doi: 10.15252/msb.20134993.

Cross-Talk-Free Multi-Color STORM Imaging Using a Single Fluorophore.

Tam J, Cordier GA, Borbely JS, Sandoval Álvarez A, Lakadamyali M.

PLoS One. 2014 Jul 7;9(7):e101772. doi: 10.1371/journal.pone.0101772. eCollection 2014.

Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation.

Hériché JK, Lees JG, Morilla I, Walter T, Petrova B, Julia Roberti M, Hossain MJ, Adler P, Fernández JM, Krallinger M, Haering CH, Vilo J, Valencia A, Ranea JA, Orengo C, Ellenberg J.

Mol Biol Cell. 2014 Jun 18. pii: mbc.E13-04-0221.

The study of severe cutaneous drug hypersensitivity reactions from a systems biology perspective.

Perkins JR, Ayuso P, Cornejo-García JA, Ranea JA.

Curr Opin Allergy Clin Immunol. 2014 Jun 5.

Cell reorientation under cyclic stretching.

Livne A, Bouchbinder E, Geiger B.

Nat Commun. 2014 May 30;5:3938. doi: 10.1038/ncomms4938.

Fluorogenic probes for live-cell imaging of the cytoskeleton.

Lukinavičius G, Reymond L, D'Este E, Masharina A, Göttfert F, Ta H, Güther A, Fournier M, Rizzo S, Waldmann H, Blaukopf C, Sommer C, Gerlich DW, Arndt HD, Hell SW, Johnsson K.

Nat Methods. 2014 May 25. doi: 10.1038/nmeth.2972.

The High Throughput Biomedicine unit at the Institute for Molecular Medicine Finland: High throughput screening meets precision medicine.

Pietiäinen V, Saarela J, Schantz-Fant CV, Turunen L, Ostling P, Wennerberg K.

Comb Chem High Throughput Screen. 2014 Mar 23.

Transfer Entropy Expressions for a Class of Non-Gaussian Distributions

Mamaghani M.J. and Tyrcha J.

Entropy 2014, 16(3), 1743-1755; doi:10.3390/e16031743

Spindle assembly on immobilized chromatin micropatterns.

Pugieux C, Dmitrieff S, Tarnawska K, Nédélec F.

Methods Enzymol. 2014;540:435-48. doi: 10.1016/B978-0-12-397924-7.00024-8.

Noise genetics: inferring protein function by correlating phenotype with protein levels and localization in individual human cells.

Farkash-Amar S, Zimmer A, Eden E, Cohen A, Geva-Zatorsky N, Cohen L, Milo R, Sigal A, Danon T, Alon U.

PLoS Genet. 2014 Mar 6;10(3):e1004176. doi: 10.1371/journal.pgen.1004176

Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells.

Keller D, Orpinell M, Olivier N, Wachsmuth M, Mahen R, Wyss R, Hachet V, Ellenberg J, Manley S, Gönczy P.

J Cell Biol. 2014 Mar 3;204(5):697-712. doi: 10.1083/jcb.201307049

Cdk1 Inactivation Terminates Mitotic Checkpoint Surveillance and Stabilizes Kinetochore Attachments in Anaphase.

Vázquez-Novelle MD, Sansregret L, Dick AE, Smith CA, McAinsh AD, Gerlich DW, Petronczki M.

Curr Biol. 2014 Feb 25. pii: S0960-9822(14)00067-0. doi: 10.1016/j.cub.2014.01.034.

Plasticity in the macromolecular-scale causal networks of cell migration.

Lock JG, Mamaghani MJ, Shafqat-Abbasi H, Gong X, Tyrcha J, Strömblad S.

PLoS One. 2014 Feb 28;9(2):e90593. doi: 10.1371/journal.pone.0090593. eCollection 2014

Mitotic Spindle Assembly on Chromatin Patterns Made with Deep UV Photochemistry.

Tarnawska K, Pugieux C, Nédélec F.

Methods Cell Biol. 2014;120:3-17.

2013

Non-parametric analysis of Granger causality using local measures of divergence

Mehrdad Jafari-Mamaghani

Applied Mathematical Sciences, Vol. 7, 2013, no. 83, 4107-4136.

Golgi depletion from living cells with laser nanosurgery.

Ronchi P, Pepperkok R.

Methods Cell Biol. 2013;118:311-24. doi: 10.1016/B978-0-12-417164-0.00019-7.

Machine learning in cell biology - teaching computers to recognize phenotypes.

Sommer C, Gerlich DW.

J Cell Sci. 2013 Nov 20.

Imaging ER-to-Golgi transport: towards a systems view.

Verissimo F, Pepperkok R.

J Cell Sci. 2013 Nov 15;126(Pt 22):5091-100. doi: 10.1242/jcs.121061.

Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay.

Pau G, Walter T, Neumann B, Heriche JK, Ellenberg J, Huber W.

BMC Bioinformatics. 2013 Oct 16;14(1):308.

Kinetic framework of spindle assembly checkpoint signalling.

Dick AE, Gerlich DW.

Nat Cell Biol. 2013 Oct 6. doi: 10.1038/ncb2842

Differential effect of actomyosin relaxation on the dynamic properties of focal adhesion proteins.

Lavelin I, Wolfenson H, Patla I, Henis YI, Medalia O, Volberg T, Livne A, Kam Z, Geiger B.

PLoS One. 2013 Sep 9;8(9):e73549. doi: 10.1371/journal.pone.0073549.

Directional tissue migration through a self-generated chemokine gradient.

Donà E, Barry JD, Valentin G, Quirin C, Khmelinskii A, Kunze A, Durdu S, Newton LR, Fernandez-Minan A, Huber W, Knop M, Gilmour D.

Nature. 2013 Sep 25. doi: 10.1038/nature12635.

Supplementary data package for Dona et al. (2013) containing example images and tables.

Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase.

Uehara R, Tsukada Y, Kamasaki T, Poser I, Yoda K, Gerlich DW, Goshima G.

J Cell Biol. 2013 Aug 19;202(4):623-36.

Control of tissue morphology by Fasciclin III-mediated intercellular adhesion.

Wells RE, Barry JD, Warrington SJ, Cuhlmann S, Evans P, Huber W, Strutt D, Zeidler MP.

Development. 2013 Aug 14.

Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation.

de Graauw M, Cao L, Winkel L, van Miltenburg MH, le Dévédec SE, Klop M, Yan K, Pont C, Rogkoti VM, Tijsma A, Chaudhuri A, Lalai R, Price L, Verbeek F, van de Water B.

Oncogene. 2013 Jun 24.

A self-organization framework for symmetry breaking in the mammalian embryo.

Wennekamp S, Mesecke S, Nédélec F, Hiiragi T.

Nat Rev Mol Cell Biol. 2013 Jul;14(7):454-61.

Insights into Polypharmacology from Drug-Domain Associations.

Moya-García AA, Ranea JA.

Bioinformatics. 2013 Jun 5.

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.

Earnshaw WC,et al. Chromosome Res. 2013 Apr;21(2):101-6

CellH5: A format for data exchange in high-content screening.

Sommer C, Held M, Fischer B, Huber W, Gerlich DW.

Bioinformatics. 2013 Apr 16.

Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping.

Laufer C, Fischer B, Billmann M, Huber W, Boutros M.

Nat Methods. 2013 Apr 7.

HD2013SGI - experimental data and a complete executable transcript (vignette) of the analysis of the HCT116 genetic interaction matrix presented in the paper.

Dynamic regulation of the structure and functions of integrin adhesions.

Wolfenson H, Lavelin I, Geiger B.

Dev Cell. 2013 Mar 11;24(5):447-58.

RNAi-Based Functional Profiling of Loci from Blood Lipid Genome-Wide Association Studies Identifies Genes with Cholesterol-Regulatory Function.

Blattmann P, Schuberth C, Pepperkok R, Runz H.

PLoS Genet. 2013 Feb;9(2):e1003338.

Cell to extracellular matrix interactions and their reciprocal nature in cancer.

van Dijk M, Göransson SA, and Strömblad S.

Exp. Cell Res. 2013 Feb 16. pii: S0014-4827(13)00062-1.

T ranscriptional networks controlling the cell cycle

Bonke M, Turunen M, Sokolova M, Vähärautio A, Kivioja T, Taipale M, Björklund M, Taipale J.

G3 (Bethesda). 2013 Jan;3(1):75-90. doi: 10.1534/g3.112.004283. Epub 2013 Jan 1.

2012

Dynamic Proteomics of Human Protein Level and Localization across the Cell Cycle

Farkash-Amar S, Eden E, Cohen A, Geva-Zatorsky N, Cohen L, Milo R, Sigal A, Danon T, Alon U.

PLoS One. 2012;7(11):e48722.

Mitotic lamin disassembly is triggered by lipid-mediated signaling.

Mall M, Walter T, Gorjánácz M, Davidson IF, Nga Ly-Hartig TB, Ellenberg J, Mattaj IW.

J Cell Biol. 2012 Sep 17;198(6):981-90.

Focal adhesion disassembly is regulated by a RIAM to MEK-1 pathway.

Coló GP, Hernández-Varas P, Lock J, Bartolomé RA, Arellano-Sánchez N, Strömblad S, Teixidó J.

J Cell Sci. 2012 Sep 3.

Mps1 promotes rapid centromere accumulation of Aurora B.

van der Waal MS, Saurin AT, Vromans MJ, Vleugel M, Wurzenberger C, Gerlich DW, Medema RH, Kops GJ, Lens SM.

EMBO Rep. 2012 Aug 31;13(9):847-54.

Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores

Wurzenberger C, Held M, Lampson MA, Poser I, Hyman AA, Gerlich DW.

J Cell Biol. 2012 Jul 23.

Semantic integration of physiology phenotypes with an application to the Cellular Phenotype Ontology.

Hoehndorf R, Harris MA, Herre H, Rustici G, Gkoutos GV.

Bioinformatics. 2012 Jul 1;28(13):1783-9.

Tandem fluorescent protein timers for in vivo analysis of protein dynamics.

Khmelinskii A, Keller PJ, Bartosik A, Meurer M, Barry JD, Mardin BR, Kaufmann A, Trautmann S, Wachsmuth M, Pereira G, Huber W, Schiebel E, Knop M.

Nat Biotechnol. 2012 Jun 24.

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway.

Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R.

Nat Cell Biol. 2012 Jun 3;14(7):764-74.

Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology.

Rojas AM, Santamaria A, Malik R, Jensen TS, Körner R, Morilla I, de Juan D, Krallinger M, Hansen DA, Hoffmann R, Lees J, Reid A, Yeats C, Wehner A, Elowe S, Clegg AB, Brunak S, Nigg EA, Orengo C, Valencia A, Ranea JA.

PLoS One. 2012;7(3):e31813.

Unsupervised modeling of cell morphology dynamics for time-lapse microscopy.

Zhong Q, Busetto AG, Fededa JP, Buhmann JM, Gerlich DW.

Nat Methods. 2012 May 27;9(7):711-3.

Molecular control of animal cell cytokinesis.

Fededa JP, Gerlich DW.

Nat Cell Biol. 2012 May 2;14(5):440-7. Review. View pdf

ESCRT-III polymers in membrane neck constriction.

Guizetti J, Gerlich DW.

Trends Cell Biol. 2012 Mar;22(3):133-40.